Clinical Trials
"An Open-label, Pilot Study evaluating the Safety
and Efficacy of Converting from Calcineurin Inhibitors to Rapamune
in established Renal Allograft Recipients on Maintenance Therapy
with Moderate Renal Insufficiency."
Funded by Wyeth Ayerst Pharmaceutical Company.
" A prospective, randomized, multicenter trial
of early corticosteroid cessation vs. long term maintenance corticosteroid
therapy in primary renal allograft recipients treatment with tacrolimus
and mycophenolate mofetil."
Funded by Fujisawa Pharmaceuticals.
" A Prospective, pilot study of early corticosteroid
cessation with Zenapax, Prograf, Cellcept, and Rapamune in High
Immunologic Risk Renal Transplant Recipients."
Funded by Roche Laboratories.
" A Prospective Pilot Study of Corticosteroid
Avoidance with Prograf, Cellcept and Rapamune that Avoids Induction
Therapy in Renal Transplant Patients."
Funded by Wyeth Ayerst Pharmaceutical Company.
" An open-label study to evaluate the safety
and efficacy of early (5 day) steroid cessation in de novo renal
allograft recipients treated with Simulect induction and Prograf
in combination with Rapamune."
Funded by Wyeth Ayerst Pharmaceutical Company.
" A multicenter, randomized, partially-blinded
study of the safety and efficacy of FTY720 combined with corticosteroids
and full or reduced dose Neoral in de novo adult renal transplant
recipients."
Funded by Novartis Pharmaceutical Company.
" Corticosteroid-free, Calcineurin-sparing Immunosuppression
Protocol for HLA-Identical Living Donor Renal Transplant Recipients."
Funded by Roche Laboratories.
" A randomized, open-label, comparative evaluation
of conversion from calcineurin inhibitors to sirolimus versus continued
use of calcineurin inhibitors in renal allograft recipients."
Funded by Wyeth Ayerst Pharmaceutical Company.
" Open-Label, Randomized, Prospective Multicenter
Study to Compare the Efficacy and Safety among Three Immunosuppressant
Treatment Regimens in Patients Receiving a Liver Transplant for
End-Stage Liver Disease Caused by Chronic Hepatitis C Infection."
Funded by Roche Laboratories.
" Rapamune Outcomes Assessment Registry."
Funded by Wyeth Ayerst Pharmaceutical Company.
" Pharmacokinetic and Pharmacodynamic evaluation
of open-label, comparative trial of two daclizumab dosing strategies
versus no induction treatment in combination with tacrolimus, mycophenolate
mofetil, and steroids for the prevention of acute allograft rejection
in simultaneous kidney/pancreas transplant recipients."
Funded by Roche Laboratories.
" A Phase 2, Randomized Multicenter, double-blind
safety study of ISA 247 and Cyclosporine in post renal Transplant
Patients."
Funded by Isotechnika.
" A Single Center, Pilot Study of Corticosteroid
Discontinuation in Liver Transplant Recipients Utilizing a Tacrolimus/Mycophenolate
Mofetil based Maintenance Immunosuppression Protocol."
Funded by Fujisawa Pharmaceuticals.
" The Effect of Immunonutrients and Monolayer
Integrity on the Transcriptional Control of Enterocyte Defenses."
Shriners of North America.
" Comparison of two vascular access grafts and
the role of arginine and Canola Oil to Prevent Graft Complications."
Funded by Atrium Medical Corporation.
" Clinical Islet Transplantation for Hypoglycemic
Unawareness and glycemic control in humans."
Funded by University Hospital/Health Alliance.
If you are interested
in participating in one of these clinical trials, please contact:
E. Steve Woodle, M.D.
Chief, Division of Transplantation
(513) 558-6001
WOODLEES@UCMAIL.UC.EDU |