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Research

Presentations & Publications

Research Division

Recent Presentations

Armour A, Schuermann T, Kagan R, Boyce S:  "Cultured skin substitutes reduce perioperative blood requirements in burn surgery." American Burn Association, San Diego, CA, March 20-23, 2007.

Armour A, Dorr B, Kagan R, Boyce T:  "Mortality of acute burns treated with cultured skin substitute." American Burn Association, San Diego, CA, March 20-23, 2007.

Armour A, Powell H, Schuermann T, Boyce S:  "Fluorescein diacetate for measurement of cell viability in cultured skin substitutes." American Burn Association, San Diego, CA, March 20-23, 2007.

Babcock GF: "Green tea polyphenols: Why you should love them." Invited visiting professor, Miami University, Department of Microbiology, Oxford, OH, October 18, 2006.

Babcock GF: "Modulation of apoptosis and the production of reactive oxygen species in human neutrophils with epigallocatechin-3-gallate (EGCG)." Invited lecture, American Association of Immunologists, Miami Beach, FL, May 18, 2007.

Bailey JK, Gottschlich MM, Allgeier CC, McClaine RJ, Kagan RJ:  "Review of practice: feeding tube placement in burn patients."  American Burn Association, March 2007.

Balasubramaniam A, Joshi R, Su C, Friend LA, James JH: "Ghrelin receptor agonist, GHRP-2, restores body weight in mice with thermal injury." American Burn Society, San Diego, CA, March 20-23, 2007.

Balasubramaniam A, Joshi R, Su C, Friend LA, James JH: "GHRP-2 attenuates burn-induced dysfunctions in rodents." American Peptide Symposium, Montreal, Canada, June 26-30, 2007.

Boulton BJ, Willson T, Goss K: "Down-regulation of the APC tumor suppressor alters mammary epithelial apoptosis and proliferation." Academic Surgical Congress, Phoenix, AZ, February 6-9, 2007.

Boyce ST:  "Transplantation of human melanocytes to restore cutaneous pigmentation." Pan American Pigment Cell Society; Cincinnati, OH, September, 2006.

Boyce ST:  "Future directions in burn wound healing." Burn Research State of the Science; Washington, DC, October, 2006.

Boyce ST:  "Opportunities and obstacles with engineered human skin." Multi-Agency Tissue Engineering Science (MATES) Workshop; Arlington, VA, February, 2007.

Boyce ST:  "Tissue engineering of human skin for burns."  Graduate Course; American Burn Association; San Diego, CA, March, 2007.

Boyce ST:  "Current status of skin substitutes."  Moderator, Sunrise symposium; American Burn Association; San Diego, CA, March, 2007.

Boyce ST:  "Basic science of burn wounds."  Moderator, Correlative session III; American Burn Association; San Diego, CA, March, 2007. 

Boyce ST:  "Engineered human skin for military burn injuries."  Advanced Technology Applications for Combat Casualty Care; St. Petersburg, FL, 2007. 

Caldwell CC, Tschop J, Goetzman H, Choi L, Reid M, Chen JF, Sitkovsky MV, Martignoni A: "Thermal injury induced lymphocyte apoptosis: A role for A2a receptors?"  7th World Congress on Trauma Sepsis and Inflammation, Munich, Germany, March 13-17, 2007.

Chance WT, Dayal R, Friend LA, Sheriff S: "Reduction of burn-induced hypermetabolism following treatment with corticotrophin releasing factor receptor 2 antisense oligonucleotide."  American Burn Association, Las Vegas, NV, 2006.

Chance WT, Xiao C, Dayal R, Sheriff S: "Alteration of NPY and Y1 receptor in dorsomedial and ventromedial areas of hypothalamus of anorectic tumor-bearing rats."  8th Biennial NPY Meeting, St. Petersburg, FL, 2006.

Chance WT, Dayal R, Friend L, Thomas I, Sheriff S: "Continuous intravenous infusion of ghrelin does not stimulate feeding in tumor-bearing rats."  Society for Neuroscience, Atlanta, GA, 2006.

Chen W, Robbins L, Keith A, Birsoy K, Roeder RG, Zhang X:  "Role of transcriptional coactivator MED1/TRAP220 in glucose homeostasis and insulin sensitivity."  Digestive Health Center Research Forum: Bench-to-Bedside Research in Pediatric Digestive Disease, Cincinnati, OH, July, 2007.

Eismann T, Huber N, Blanchard J, Wyder M, Greis KD, Lentsch AB: "Changes in the liver mitochondrial proteome after ischemia/reperfusion." Experimental Biology, Washington DC, April 28-May 2, 2007.

Galloway E, Wong HR, Schuster R, Lentsch AB: "Stimulation of CXC chemokine production in hepatocytes by HSP-70."  Shock Society, Baltimore, MD, June 9-12, 2007.

Huber N, Eismann T, Schuster R, Lentsch AB: "Analysis of liver gene expression during ischemia." Experimental Biology, Washington DC, April 28-May 2, 2007.

Kadekaro AL, Supp DM, Kavanagh RJ, Terzieva S, Sartor M, Tomlinson C, Abdel-Malek Z:  "Microarray analysis reveals significance of a-MSH in counteracting the UV effects on human melanocytes."  Society for Investigative Dermatology, Philadelphia, PA, 2006.

Kadekaro A-L, Supp DM, Kavanagh R, Terzieva S, Sartor M, Tomlinson C, Abdel-Malek Z:  "Microarray analysis reveals the role of α-MSH in counteracting the UV effects on human melanocytes."  PanAmerican Society for Pigment Cell Research, Cincinnati, OH, 2006.

Kadekaro AL, Supp DM, Kavanagh R, Koshoffer A, Boissy R, Abdel-Malek ZA: "Transfection with the wild type MC1R normalizes the DNA damage response of human melanocytes expressing non-functional MC1R."  Society for Investigative Dermatology, Los Angeles, CA, 2007.

Lentsch AB: "NF-kB in ischemia/reperfusion." American Association of Liver Diseases, Vascular Biology and Pathobiology of the Liver, Atlanta, GA, June 2-4, 2007.

Lentch AB:  Symposia Presentation, "Lung inflammation caused by distant ischemia." 7th World Congress on Trauma, Shock, Inflammation and Sepsis, Munich, Germany, March 13-17, 2007.

Lentch AB:  Symposia Presentation, "NF-kB in ischemia-reperfusion." Stratton Basic Research Conference, American Association for the study of Liver Diseases, Atlanta, GA, June 2-4, 2007.

McClaine RJ, Lowy AM, Gelrud A, Schmulewitz N, Chauhan S, James LE, Sussman JJ, Ingraham AM, Matthews JB, Ahmad SA:  "A comparison of pancreaticoduodenectomy and duodenal sparing head resection for the treatment of chronic pancreatitis."  Pancreas Club, May 2007.

Neely AN, Plessinger RT, Stamper B, Kagan RJ:  "Efficacy of a process for delivering clean skin allografts."  American Association of Tissue Banks, San Diego, CA, September 9-12, 2006.

Neely AN, Mayes T, Gardner J, Kagan RJ, Gottschlich MM:  "A microbiological study of enteral feeding hang time in a burn hospital: Can feeding costs be reduced without compromising patient safety?"  Eastern Great Lakes Burn Study Group, Dayton, OH, October 26-27, 2006.

Neely AN, Regnold L, Hayes S, Gardner J, Cahill T:  "Redesign of portable suction equipment cases."  Greater Cincinnati Health Council Solutions 2007 Conference, Covington, KY, February 28, 2007.

Neely A, Plessinger R, Stamper B, Kagan R: "Can contamination on a patient’s allograft be traced back to the allograft donor?" American Burn Association, San Diego, CA, March 20-23, 2007.

Powell HM, Supp DM, Boyce ST: "Bioengineered skin substitutes fabricated with electrospun collagen decrease in vivo wound contraction."  Tissue Engineering and Regenerative Medicine International Society, Toronto, Ontario, Canada, 2007.

Ogle CK: "Thermal injury and sepsis cause an increase in monocytes that are the TNF." 7th World Congress on Trauma, Shock, Inflammation and Sepsis, Munich, Germany, March, 2007.

Robinson C, Cave C, Lentsch AB, Solomkin JS: "Trafficking and compartmentalization of integrins and oxidase components in a model of neutrophil priming and subsequent destination-based activation." Surgical Infection Society, Toronto, Canada, April 18-20, 2007.

Sheriff S, Kadeer N, Yahya A, Li BG, Chance WT, Kagan RJ, Fang CH: "Urocortin-induced inhibition of muscle protein breakdown in sepsis."  American Burn Association, Las Vegas, NV, 2006.

Supp DM:  "Scar biology and management." Invited Lecturer, American Burn Association Annual Meeting Post-Graduate Course, San Diego, CA, March 20-23, 2007.

Supp DM, Smiley AK, Gardner J, Klingenberg J, Boyce ST, Neely A:  "Gene transfer of human beta defensin 4 to increase antimicrobial activity of primary cultured epidermal keratinocytes."  Wound Healing Society, Scottsdale, AZ, 2006.

Supp DM, McFarland KM, Klingenberg JM:  "Expression of antimicrobial proteins and members of the Toll-like receptor/nuclear factor B pathways in engineered human skin."  American Burn Association, San Diego, CA, March 20-23, 2007.

Taylor JA, Bernabe KQ, Guo J, Warner BW:  "Epidermal growth factor receptor-directed enterocyte proliferation does not induce Wnt pathway transcription." Annual Meeting of the Section on Surgery of the American Academy of Pediatrics, Atlanta, GA, October 7-10, 2006.

Tschop J, Martignoni A, Goetzman H, Choi L, Reid M, Caldwell CC: "CD4 expressing cells are early mediators of the innate immune system during sepsis."  7th World Congress on Trauma Sepsis and Inflammation, Munich, Germany, March 13-17, 2007.

Tschop J, Martignoni A, Goetzman H, Choi L, Reid M, Caldwell CC: "Neutrophil function and recruitment is mediated by the early actions of gamma delta T-cells during sepsis such that mortality and bacterial load is decreased."  Surgical Infection Society, Toronto, Ontario, April 18-20, 2007.

Vaikunth S, Marwan A, Parvadia J, Ripberger M, Kalinowska B, Uzvolgyi E, Supp AP, Boyce ST, Crombleholme T, Supp DM:  "Endothelial progenitor cells participate in neovascularization and engraftment of cultured skin substitutes.  American College of Surgeons Clinical Congress, Chicago, IL, 2006.

Vaikunth S, Marwan A, Parvadia J, Maldonado A, Ripberger M, Kalinowska B, Supp A, Boyce ST, Crombleholme T, Supp DM:  "Cultured skin substitutes (CSS): An ideal model for the study of angiogenesis and vasculogenesis."  Winner, Young Investigator’s Award (S. Vaikunth).  Wound Healing Society, Tampa, FL, 2007. 

Waltz SE, Zinser GM, Leonis MA, Toney K, Peace BE, Beauman SR, Collins MH:  "Mammary-specific Ron receptor overexpression induces highly metastatic mammary tumors associated with B-catenin activation."  Abstract, 25th International Congress of the International Association of Breast Cancer Research, Montreal, Quebec, September 15-18, 2006.  

Waltz SE:  "The Ron receptor tyrosine kinase in mammary biology."  Invited Speaker, McGill University Cancer Centre, Montreal, Quebec H3G 1Y6, October 12, 2006.

Waltz SE:  "The Ron receptor tyrosine kinase in mammary biology."  Biogen Idec, Cambridge, MA, November 2, 2006.

Waltz SE:  "Ron receptor signaling and mammary homeostasis." Molecular Physiology. University of Cincinnati, Cincinnati, OH, December, 2006.

Waltz SE:  "The Ron receptor tyrosine kinase in breast development and cancer."  Stony Brook University, New York, April 23, 2007.

Wang SC:  "Regulation of PCNA function by tyrosine phosphorylation." Invited speaker, Department of Environmental Health, University of Cincinnati, Cincinnati, OH, March 28, 2007.

Wang SC:  "The death of a ring." Invited speaker, Department of Surgery Research Conference, University of Cincinnati, Cincinnati, OH, April 6, 2007.

Wang SC:  "The role of proliferating cell nuclear antigen (PCNA) in cancer progression and chemotherapy." Invited speaker, Surgical Grand Rounds, University of Cincinnati, OH, April 11, 2007.

Wang SC:  "Nuclear localization of EGFR and PCNA." Invited speaker, Oncology Retreat, Department of Surgery, Oncology Research Group, University of Cincinnati, OH, June 15, 2007.

Worrell RT:  "NKCC1 internalization: A potential hot topic."  Fluxes & Barriers Seminar, September 13, 2006.

Worrell RT: "Ammonium, not just for cleaning: Role in the colon." Department of Biology, Northern Kentucky University, October 11, 2006.

Worrell RT:  "Epithelial cell specific capsaicin effect on Cl- secretion and NKCC1." Poster, Ohio Physiological Society, November 4, 2006.

Worrell RT:  "Hot peppers and colonic secretion."  College of Pharmacy, University of Cincinnati, November 11, 2006.

Worrell RT:  "Hot peppers and colonic secretion: What an undergraduate can do in a summer."  Key Note Speaker, BBB Biology Honor Society Meeting, Thomas More University, April 27, 2007.

Worrell RT:  "Epithelial cell specific capsaicin effect on Cl- secretion and NKCC1." Experimental Biology, April 29, 2007.

Worrell RT:  "Ammonium secretion in colon involves NKCC1 and Rh glycoproteins."  Experimental Biology, May 1, 2007.

Worrell RT:  "Ammonium, not just for cleaning: Role in the colon." Systems Biology & Physiology Retreat, May 22, 2007.

Worrell RT:  "Trauma and the intestinal barrier: The second-hit hypothesis."  Lake Cumberland Biological Transport Group Meeting, June 18, 2007.

Worrell RT:  "Epithelial cell specific capsaicin effect on Cl- secretion."  Lake Cumberland Biological Transport Group Meeting, June 19, 2007.

Zinser GM, Waltz SE: "Vitamin D3 induces growth inhibition of murine cell lines isolated from Ron receptor overexpressing mammary tumors." Third Annual Interdisciplinary Women's Health Research Symposium, Washington, DC, November 14-16, 2006.

 

Recent Publications

Abdala-Valencia H, Earwood J, Bansal S, Jansen M, Babcock GF, Garvy B, Willis-Karp M, Cook-Mills JM.  Non-hematopoietic NADPH oxidase regulation of lung eosinophilia and airway hyper-responsiveness in experimentally-induced asthma. Am J Physiol (Lung Cell Mol Physiol), Feb. 9, 2007 [Epub ahead of print].

Abdala-Valencia H, Earwood J, Babcock GF, Garvy V, Wills-Karp M, Cook-Mills J.  Non-hematopoietic NADPH oxidase regulation of lung eosinophilia and airway hyper-responsiveness in experimentally-induced asthma [abstract].  J Immunol 178:98.3, 2007.

Abdel-Malek ZA, Kadekaro AL, Kavanagh RJ, Todorovic A, Koikov LN, McNulty JC, Jackson PJ, Millhauser GL, Schwemberger S, Babcock GF, Hasdell-Luevano C, Knittlel JJ. Melanoma prevention strategy based on using tetrapeptide a-MSH analogs that protect human melanocytes from UV-induced DNA damage and cytotoxicity. FASEB J 20:1561-1563, 2006.

Amlal H, Sheriff S, Faroqui S, Ma L, Barone S, Petrovic S, Soleimani M. Regulation of acid-base transporters by vasopressin in the kidney collecting duct of Brattleboro rat. Am J Nephrol 26:194-205, 2006.

Amlal H, Faroqui S, Balasubramaniam A, Sheriff S. Estrogen up-regulates neuropeptide YY1 receptor expression in a human breast cancer cell line. Cancer Res 66:3706-3714, 2006.

Babcock GF, Osterburg A, Schwemberger S.  Regulation of neutrophil function by HSP72 and GM-CSF [abstract].  J Immunol 176:S82, 2006.

Babcock GF, Osterburg AR, Schwemberger S, Hyon SH, Koizumi T. Modulation of apoptosis and the production of reactive oxygen species in human neutrophils with epigallocatechin-3-gallate (EGCG) [abstract].  J Immunol 178:101.6, 2007.

Balasubramaniam A, Mullins DE, Lin S, Zhai W, Tao Z, Dhawan VC, Guzzi M, Knittel JJ, Slack K, Herzog H, Parker EM. Neuropeptide Y (NPY) Y4 receptor selective agonists based on NPY (32-36): Development of an anorectic Y4 receptor selective agonist with picomolar affinity. J Med Chem 49:2661-2665, 2006.

Balasubramaniam A, Wood S, Joshi R, Su C, Friend LA, Sheriff S, James JH. Ghrelin stimulates food intake and growth hormone release in rats with thermal injury: Synthesis of ghrelin. Peptides 27:1624-1631, 2006.

Balasubramaniam A, Joshi R, Su C, Friend LA, James JH.  Neuropeptide Y (NPY) Y2 receptor-selective agonist inhibits food intake and promotes fat metabolism in mice: Combined anorectic effects of Y2 and Y4 receptor-selective agonists. Peptides 28:235-240, 2007.

Balasubramaniam A, Joshi R, Su C, Friend LA, James JH.  GHRP-2 Attenuates Burn-Induced Dysfunctions in Rodents.  In: Peptides for Youth (Escher E, Lubell WD, eds). American Peptide Society, 2007.

Barai ND, Boyce ST, Hoath SB, Visscher MO, Kasting GB.  Improved barrier function observed in cultured skin substitutes under anchored conditions.  Skin Res Tech 12:1-7, 2006.

Barai ND, Supp AP, Boyce ST, Kasting GB, Visscher MO.  Improvement of barrier properties in cultured skin substitutes after grafting onto athymic mice.  Skin Pharmacol Physiol 20:21-28, 2007.

Bernal NP, Stehr W, Coyle R, Erwin CR, Warner BW. EGF receptor signaling regulates Bax and Bcl-w expression and apoptotic responses during intestinal adaptation in mice. Gastroenterology 130:412-423, 2006.

Bernal NP, Stehr W, Zhang Y, Profitt S, Erwin CR, Warner BW. Combined pharmacotherapy that increases proliferation and decreases apoptosis optimally enhances intestinal adaptation. J Pediatr Surg 41:719-724, 2006.

Bommireddy R, Pathak LJ, Martin J, Ormsby I, Engle SJ, Boivin GP, Babcock GF, Eriksson AU, Singh RR, Doetschman T. Self-antigen recognition by TGF-beta1-deficient T cells causes their activation and systemic inflammation. Lab Invest. 86:1008-1019, 2006.

Bommireddy R, Pathak LJ, Martin J, Boivin GP, Babcock GF, Doetschman T.  Self-antigen recognition causes T-cell activation and systemic inflammation in TGF?1-deficient mice [abstract].  J Immunol 176:S282, 2006.

Bommireddy R, Babcock GF, Singh RR, Doetschman T.  TGF-beta1 is not essential for generation and maintenance of natural Treg cells [abstract].  J Immunol 178:128.10, 2007.

Boyce ST, Anderson BA, Rilo HL.  Quantitative assay for quality assurance of human cells for clinical transplantation.  Cell Transplant 15:169-174, 2006. 

Boyce ST, Kagan R, Greenhalgh D, Yakuboff K, Warner P, Palmieri T, Warden G. Cultured skin substitutes reduce donor skin harvesting in treatment of excised, full-thickness burns. J Trauma 60:821-829, 2006.

Caldwell CC, Tschoep J, Lentsch AB.  Lymphocyte function during ischemia/reperfusion injury. J Leukocyte Biol 82:457-464, 2007.

Chance WT, Dayal R, Friend LA, Sheriff S. Possible role of CRF peptides in burn-induced hypermetabolism. Life Sci 78:694-703, 2006.

Chan EL, Peace BE, Toney K, Kader SA, Pathrose P, Collins MH, Waltz SE.  Homozygous K5Cre transgenic mice have wavy hair and accelerated malignant progression in a murine model of skin carcinogenesis.  Mol Carcinog 46:49-59, 2007.

Chance WT, Sheriff S, Dayal R, Friend LA, Thomas I, Balasubramaniam A. The role of polyamines in glucagon-like peptide-2 prevention of TPN-induced gut hypoplasia. Peptides 27:883-892, 2006.

Chance WT, Xiao C, Dayal R, Sheriff S.  Alteration of NPY and Y1 receptor in dorsomedial and ventromedial areas of hypothalamus of anorectic tumor-bearing rats.  Peptides 28:295-301, 2006.

Chance WT, Dayal R, Friend LA, Thomas I, Sheriff S. Mediation of burn-induced hypermetabolism by CRF receptor-2 activity.  Life Sci 80:1064-1072, 2007.

Chance WT, Dayal R, Friend LA, Thomas I, Sheriff S. Continuous intravenous infusion of ghrelin does not stimulate feeding in tumor-bearing rats. Nutrition and Cancer, in press, 2007.

Chen IF, Ou-Yang F, Hung JY, Liu JC, Wang H, Wang SC, Hou MF, Hortobagyi GN, Hung MC. AIM2 suppresses human breast cancer cell proliferation in vitro and mammary tumor growth in a mouse model. Molecular Cancer Therapy 5:1-7, 2006.

DiGiandomenico A, Rao J, Harcher K, Zaidi TS, Gardner J, Neely AN, Pier GB, Goldberg JB.  Protection against distinct Pseudomonas aeruginosa infections after intranasal vaccination. Proc Natl Acad Sci 104:4624-4629, 2007.

Dugan L, Schwemberger S, Noel G, Babcock GF, Ogle C, Horseman N.  Chronic psychogenic stress prior to burn injury has differential effects on the bone marrow and cytokine responses. Exp Biol Med 232:253-261, 2007.

Erwin CR, Jarboe MD, Sartor MA, Medvedovic M, Stringer K, Warner BW, Bates MD. Developmental characteristics of adapting mouse small intestine crypt cells. Gastroenterology 130:1324-1332, 2006.

Fang CH, Li B, James JH, Yahya A, Kadeer, N, Guo X, Xiao C, Supp DM, Kagan R, Hasselgren PO, Sheriff S.  Gsk-3β activity is increased in skeletal muscle after burn injury in rats.  Am J Physiol, in press.

Gassama-Diagne A,Yu W, ter Beest M, Martin-Belmonte F, Kierbel A, Engel J, Mostov K. Phosphatidylinositol-3,4,5-trisphosphate regulates the formation of the basolateral plasma membrane in epithelial cells. Nature Cell Biol, in press.

Gibran NS, Boyce ST, Greenhalgh DG.  Cutaneous wound healing.  J Burn Care Res 28:577-579, 2007.

Greenhalgh DG, Saffle J, Holmes J IV, Gamelli R, Palmiere TL, Horton J, Tompkins R, Traber D, Mozingo D, Deitch E, Goodwin C, Herndon D, Gallagher J, Sanford A, Jeng J, Ahrenholz D, Neely AN, O’Mara MS, Wolf SE, Purdue G, Garner W, Yowler C, Latenser B.  ABA Consensus Conference to Define Sepsis and Infection in Burns.  J Burn Care Res, in press.

Hauser JE, Kadekaro AL, Kavanagh RJ, Wakamatsu K, Terzieva S, Schwemberger S, Babcock GF, Rao MB, Ito S, Abdel-Malek ZA. Melanin content and MC1R function independently affect UVR-induced DNA damage in cultured human melanocytes. Pigment Cell Res 19:303-314, 2006.

Healy DP, Gardner JC, Puthoff BK, Kagan RJ, Neely AN.  Antibiotic-mediated bacterial filamentation: A potentially important laboratory phenomenon.  Clin Microbiol Newsl 29:22-24, 2007.

Huang JH, Cardenas-Navia LI, Caldwell CC, Plumb TJ, Radu CG, Rochal PN, Wilder T, Bromberg JS, Cronstein BN, Sitkovsky M, Dewhirst MW, Dustin ML.  Requirements for T-lymphocyte migration in explanted lymph nodes.  J Immunol 178:7747-7755, 2007.

Hullin R, Matthes J, von Vietinghoff S, Bodi I, Rubio M, D’Souza K, Khan IF, Rottlander D, Hoppe UC, Mohacsi P, Schmitteckert E, Gilsbach R, Bunemann M, Hein L, Schwartz A, Herzig S.  Increased expression of the auxilliary beta-2-subunit of ventricular L-type Ca 2+ channels leads to single-channel activity characteristic of heart failure.  PLoS ONE 2:e292, 2007.

Husted TL, Blanchard J, Schuster R, Shen H, Lentsch AB. Potential role for IL-23 in hepatic ischemia/reperfusion injury. Inflammation Res 55:177-178, 2006.

Husted TL, Lentsch AB. The role of cytokines in pharmacological modulation of ischemia/reperfusion injury. Curr Pharmaceut Design 12:2867-2873, 2006.

Ishiguro H, Namkung W, Yamamoto A, Wang Z, Worrell RT, Lee MG, Solemani M.  Effect of Slc26a6 deletion on apical Cl-/HCO3- exchanger activity and cAMP-stimulated bicarbonate secretion in pancreatic duct. Am J Physiol (Gastrointest Liver Physiol) 292:G447-G455, 2006.

Johnson SR, Valente JF, Alexander JW, Ogle CK, Custer D, Szabo C, Salzman AL. Evidence for the formation of peroxynitrite in a rat model of acute allograft rejection. Crit Care Med, in press.

Jois SDS, Nagarajarao LM, Prabhakaran M, Balasubramaniam A. Modeling of neuropeptide receptors Y1, Y4, Y5 and docking studies with neuropeptide antagonist analogues: Implications for selectivity. J Biomolecular Structure Dynamics 22:497-508, 2006.

Kalyanaraman B, Boyce ST.  Assessment of an automated bioreactor to propagate and harvest keratinocytes for fabrication of engineered skin substitutes.  Tissue Engineering 13:983-993, 2007.

Kaplan AJ, Wu JZ, Ogle CK, Peddi VR, First MR, Alexander JW, Munda R, Demmy A, Valente JF. The incidence and significance of the G1691A mutation of coagulation factor V in recipients of kidney pancreas transplants. Clinic Transplant, in press.

Knauf JA, Ouyang B, Fukasawa K, Babcock G, Fagin JA. Oncogenic ras induces accelerated transition through G2/M and promotes defects in the G2 DNA damage and mitotic spindle checkpoints. J Biol Chem 281:3800-3809, 2006.

Koizumi T, Leonard CD, Schwemberger S, Babcock GF. Epigallocatechin-3-gallate modulates neutrophil apoptosis and the production of reactive oxygen species [abstract].  J Burn Care Res 27:S54, 2006. 

Kuboki S, Okaya T, Blanchard J, Schuster R, Denenberg A, Wong HR, Lentsch AB. Hepatocyte NF-kB activation is hepatoprotective during ischemia/reperfusion injury and is augmented by ischemic hypothermia. Am J Physiol (Gastrointest Liver Physiol) 292: G201-G207, 2007.

Kuboki S, Schuster R, Blanchard J, Pritts TA, Wong H.R, Lentsch AB.  Role of heat shock protein 70 in hepatic ischemia/reperfusion injury in mice.  Am J Physiol (Gastrointest Liver Physiol) 292: G1141-G1149, 2007.

Kuboki S, Shin T, Huber N, Eismann T, Galloway E, Schuster R, Blanchard J, Zingarelli B, Lentsch AB.  Peroxisome proliferator-activated receptor-gamma protects against hepatic ischemia/reperfusion injury.  Hepatology, in press, 2007.

Kulesekara H, Lee V, Brencic A, Liberati N, Urbach J, Miyata S, Lee DG, Neely AN, Haykawa Y, Ausubel FM, Lory S.  Systemic analysis of Pseudomonas aeruginosa proteins with diguanylate cyclase and phosphodiesterase domains reveals a role for cyclic di-GMP in virulence. Proc Natl Acad Sci 103:2839-2844, 2006.

Lentsch AB, Pathrose P, Kuboki S, Kader S, Collins MH, Waltz SE.  RON regulates acute lung injury by inhibiting NF-kB activation. Shock 27:274-280, 2007.

Lentsch AB. CXC chemokines and prostate cancer: growth regulators and potential biomarkers. Future Oncology 2:651-658, 2006.

Mak GZ, Kavanaugh GM, Buschmann MM, Stickley SM, Koch M, Goss KH,Waechter H, Zuk A, Matlin KS. Regulated synthesis and functions of Laminin 5 in polarized Madin-Darby Canine Kidney (MDCK) epithelial cells. Molecul Biol Cell 17:3664-3677, 2006.

Mallakin A, Kutcher LW, McDowell SA, Kong S, Schuster R, Lentsch AB, Aronow BJ, Leikauf GD, Waltz SE. Gene expression profiles of Mst1r deficient mice during nickel-induced acute lung injury. Am J Respir Cell Molec Biol 34:15-27, 2006.

Markey MP, Bergseid J, Bosco EE, Stengel K, Xu H, Mayhew CN, Schwemberger SJ, Braden WA, Jiang Y, Babcock GF, Jegga AG, Aronow BJ, Reed MF, Wang JY, Knudsen ES. Loss of the retinoblastoma tumor suppressor: Differential action on transcriptional programs related to cell cycle control and immune function. Oncogene, April 23, 2007 [Epub ahead of print].

Martignoni A, Tschop J, Goetzman HS, Choi LG, Reid MD, Johannigman JA, Lentsch AB, Caldwell CC.  CD4 expressing cells are early mediators of the innate immune system during sepsis.  Shock, in press.

McClaine RJ, Uemura K, McClaine DJ, Shimazutsu K, de la Fuente SG, Manson RJ, White WD, Eubanks WS, Benni PB, Reynolds JD. A description of the preterm fetal sheep systemic and central responses to maternal general anesthesia.  Anesth Analg 104:397-406, 2007.

Mordan-McCombs S, Brown T, Zinser G, Welsh J, Tenniswood M.  Dietary calcium does not affect prostate tumor progression in LPB-Tag transgenic mice.  J Steroid Biochem Molec Biol 103:747-751, 2007.

Nakagawa-Goto K, Yamada K, Nakamura K, Chen TH, Chiang PC, Bastow KF, Wang SC, Spohn B, Hung MC, Lee FY, Lee FC, Lee KH. Antitumor agents. 258. Syntheses and evaluation of dietary antioxidant-taxoid conjugates as novel cytotoxic agents. Bioorganic & Medicinal Chemistry Letters, in press.

Neely AN, Mayes T, Gardner J, Kagan RJ, Gottschlich MM.  A microbiologic study of enteral feeding hang time in a burn hospital: Can feeding costs be reduced without compromising patient safety?  Nutr Clin Pract 21:610-616, 2006.

Neely AN, Regnold LA, Hayes S, Gardner J, Cahill TJ.  Redesign of portable suction equipment cases: An engineering approach to a disinfection problem.  Am J Infect Control 34:291-294, 2006.

Neely AN, Plessinger RT, Stamper B, Kagan RJ.  Can contamination of a patient’s allograft be traced back to the allograft donor?  J Burn Care Res, in press.

Neely AN.  Masks, gloves and gowns protect staff and shield patients from potentially harmful bacteria.  Outpatient Surgery Magazine, in press.

Noel G, Guo X, Wang Q, Schwemberger S, Byrum D, Ogle CK. Post-burn monocytes are the major producers of TNF in the heterogeneous splenic macrophage population. Shock 27:312-319, 2007.

Noel G, Byrum D, Guo X, Caldwell C, Martignoni A, Ogle CK.  Effect of thermal injury upon the inflammatory potential of splenic myeloid subpopulations. Shock, in press.

Noel G, Osterburg A, Wang Q, Guo X, Byrum D, Schwemberger S, Goetzman H, Caldwell CC, Ogle CK.  Thermal injury elevates the inflammatory monocyte subpopulation in multiple compartments.  Shock, in press.

O’Brien LE, Yu W, Tang K, Jou TS, Zegers MMP, Mostov KE. Morphological and biochemical analysis of Rac1 in three-dimensional epithelial cell cultures. Methods Enzymol 406:676-691, 2006.

Okaya T, Kuboki S, Blanchard J, Schuster R, Denenberg A, Wong HR, Lentsch AB. Regulation of hepatic NF-kB activation during reperfusion after normothermic and hypothermic ischemia. Shock 25 (Suppl 1):38, 2006.

Osterburg A, Schwemberger S, Babcock GF.  Effects of heat shock protein 72 on neutrophil function [abstract].  Proc 23rd Int Soc Anal Cytol 23:142, 2006.

Osterburg A, Schwemberger S, Babcock GF.  Effects of heat shock protein 72 on neutrophil function [abstract]. Proc Great Lakes Int Imag Flow Cytometry Assoc 15:26, 2006.

O’Toole JM, Rabenau KE, Burns K, Lu D, Mangalampalli V, Balderes P, Covino N, Bassi R, Gottfredson KJ, Thobe MN, Chen Y, Li Y, Hicklin DJ, Zhu Z, Waltz SE, Hayman MJ, Ludwig DL, Pereira DS.  Therapeutic implications of a human antibody to the macrophage-stimulating protein receptor tyrosine kinase (RON), a c-Met family member.  Cancer Research 66:9162-9170, 2006.

Parker SL, Parker MS, Sah R, Balasubramaniam A, Sallee FR. Self-regulation of agonist activity at the Y receptors. Peptides 28:203-213, 2007.

Potoka DA, McClaine R, Upperman JS.  Pediatric cystadenoma of the mesocolon.  J Pediatr Surg 41:e63-364, 2006.

Powell HM, Boyce ST.  EDC crosslinking increases strength and stability of cultured skin substitutes.  Biomaterials 27:5821-5827, 2006.

Powell HM, Boyce ST.  Wound closure with EDC-crosslinked cultured skin substitutes grafted to athymic mice.  Biomaterials 28:1084-1092, 2007. 

Powell HM, Boyce ST.  Fiber density of electrospun gelatin scaffolds regulates morphogenesis of dermal-epidermal skin substitutes.  J Biomed Mater Res, in press. 

Powell HM, Boyce ST.  Advanced designs of engineered skin substitutes.  In: Biomaterials for Treating Skin Loss (Orgill D, Blanco C, eds).  Abington, UK: Woodhead Publishing, in press. 

Rajan S, Williams S, Jagatheesan G, Ahmed R, Fuller G, Schwartz A, Aronow B, Wieczorek D.  Microarray analysis of gene expression during early stages of mild and severe cardiac hypertrophy.  Physiol Genomics 27:309-317, 2006.

Robinson CT, Cave CM, Umanskiy K, Lentsch AB, Solomkin JS. Neutrophils degranulate and prime after partial cholesterol depletion. Shock 25 (Suppl 1):27, 2006.

Robinson CT, Cave CM, Lentsch AB, Solomkin JS. Neutrophils degranulate and prime after partial cholesterol depletion: involvement of phosphatase SHP-1. Shock 25 (Suppl 1):84-85, 2006.

Saari JT, Wold LE, Duan J, Ren J, Carlson HL, Bode AM, Lentsch AB, Zeng H, Schuschke DA. Cardiac nitric oxide synthases are elevated in dietary copper deficiency. J Nutrit Biochem 18: 443-448, 2007.

Sah R, Parker SL, Sheriff S, Eaton K, Balasubramaniam A, Sallee FR.  Interaction of NPY compounds with rat glucocorticoid-induced receptor (GIR) reveals similarity to the NPY-Y2 receptor. Peptides 28:302-309, 2007.

Schweinfest CW, Spyropoulos DS, Henderson KW, Ho-Kim J, Chapman JM, Barone S, Worrell RT, Wang Z, Soleimani M.  SLC26a3 (DRA) deficient mice display chloride losing diarrhea, enhanced colonic proliferation and distinct upregulation of ion transporters in the colon. J Biol Chem 281:37962-37971, 2006.

Shah S, Islam MN, Dakshanamurthy S, Rizvi I, Rao M, Herrell R, Zinser G, Valrance M, Aranda A, Moras D, Norman A, Welsh J, Byers SW.  The molecular basis of Vitamin D receptor and beta-catenin crossregulation. Molecular Cell 21:799-809, 2006.

Shen H, Schuster R, Stringer KF, Waltz SE, Lentsch AB. The Duffy antigen/receptor for chemokines (DARC) regulates prostate tumor growth. FASEB J 20:59-64, 2006.

Shen H, Schuster R, Lu B, Waltz SE, Lentsch AB. Critical and opposing roles of the chemokine receptors CXCR2 and CXCR3 in prostate tumor growth. The Prostate 66:1721-1728, 2006.

Shivakumar P, Sabla G, Mohanty S, McNeal M, Ward R, Stringer K, Caldwell C, Chougnet C, Bezerra JA. Effector role of neonatal hepatic CD8+ lymphocytes in epithelial injury and autoimmunity in experimental biliary atresia. Gastroentrology, in press, 2007.

Smiley AK, Klingenberg JM, Boyce ST, Supp DM.  Keratin expression in cultured skin substitutes suggests that the hyperproliferative phenotype in vitro is normalized after grafting.  Burns 32:135-138, 2006. 

Smiley AK, Gardner J, Klingenberg JM, Neely AN, Supp DM. Expression of human beta defensin 4 in genetically modified keratinocytes enhances antimicrobial activity.  J Burn Care Res 28:127-132, 2007.

Solomkin JS, Robinson CT, Cave CM, Umanskiy K, Matlin K, Williams MA, Lentsch AB. Formation of focal adhesion-like structures in human neutrophils after severe injury: Triggering of a tissue-phase response in the vascular space. Shock 25:440-445, 2006.

Solomkin JS, Robinson CT, Cave CM, Ehmer B, Lentsch AB. Alterations in membrane cholesterol cause mobilization of lipid rafts from specific granules and primes human neutrophils for enhanced adherence-dependent oxidant production.  Shock 28: 334-338, 2007.

Stehr W, Bernal NP, Bernabe KQ, Erwin CR, Warner BW. Absent STAT1 expression perturbs adaptation and apoptosis after massive intestinal resection. J Pediatr Surg 41:713-718, 2006.

Stehr W, Bernal NP, Erwin CR, Bernabe KQ, Guo J, Warner BW. Roles for p21[waf1/cip1] and p27[kip1] during the adaptation response to massive intestinal resection. Am J Physiol Gastrointest Liver Physiol 290:G933-G941, 2006.

Supp DM, Boyce ST.  Bioengineering of human skin substitutes.  In: Biomedical Engineering Handbook (Fisher JP, Mikos AG, eds).  Boca Raton, FL: CRC Press, 2006.

Supp DM. Gene therapy to fight infection in skin transplants.  Pharmacogenomics 8:483-486, 2007.

Supp DM, Neely AN.  Cutaneous antimicrobial gene therapy: engineering human skin replacements to combat wound infection.  Expert Rev Dermatol, in press.

Swope VB, Supp AP, Schwemberger S, Babcock GF, Boyce S. Increased expression of integrins and decreased apoptosis correlated with increased melanocyte retention in cultured skin substitutes. Pigment Cell Res 19:424-433, 2006. 

Thiel M, Caldwell CC, Kreth S, Kuboki S, Lukashev D, Chen P, Smith P, Ohta A, Lentsch AB, Sitkovsky M. Targeted deletion of HIF-1-alpha gene in T cells prevents their inhibition in hypoxic inflamed tissues and improves septic mice survival. PLoS One, in press.

Thomas RM, Toney K, Fenoglio-Preiser C, Revelo P, Hingorani S, Tuveson D, Waltz SE, Lowy AM. The RON receptor tyrosine kinase mediates oncogenic phenotypes and has increased expression during the progression of pancreatic cancer. Cancer Res 67:6075-6082, 2007.

Toledo-Pereyra LH, Lopez-Neblina F, Lentsch AB, Anaya-Prado R, Romano SJ, Ward PA. Selectin inhibition modulates NF-kB and AP-1 signaling after liver ischemia/reperfusion.  J Invest Surg 19:313-322, 2006.

Vesper SJ, Rogers ME, Neely AN, Haugland RA.  Opportunistic Aspergillus pathogens measured in home and hospital tap water by quantitative PCR (QPCR).  J Water Health 5:427-431, 2007.

Wang Q, Guo XL, Wells-Byrum D, Noel G, Ogle C. Heat shock stress ameliorates cytokine mixture-induced permeability by down-regulating the nitric oxide and signal transducer and activator of transcription (STAT) pathways in Caco-2 cells. 27:179-185, 2007.

Wang Q, Guo XL, Wells-Byrum D, Noel G, Ogle C.  Cytokine-induced epithelial changes are regulated by the activation of P38.  Shock, in press.

Wang SC, Xia W, Lien HC, Pan Y, Sahin A, Kuo YH, Chang KJ, Zhou X, Wang H, Yu Z, Hortobagyi G, Shi DR, Hung MC. Expression of PEA3 and Lack of Correlation between PEA3 and HER-2/neu Expression in Breast Cancer. Breast Cancer Research and Treatment 98:295-301, 2006.

Wang SC, Nakajima Y, Yu YL, Xia W, Chen CT, Li LY, Hawke DH, Kobayashi R, Hung MC. Tyrosine phosphorylation controls PCNA function through protein stability. Nature Cell Biology 8:1359-1368, 2006.

Wetherill YB, Hess-Wilson JK, Comstock CE, Shah SA, Buncher CR, Sallans L, Limbach PA, Schwemberger S, Babcock GF, Knudsen K.  Bisphenol A facilitates bypass of androgen ablation therapy in prostate cancer. Mol Cancer Therapeut 5:3181-3190, 2006.

Wetzel CC, Leonis MA, Dent A, Olson MA, Longmeier AM, Ney PA, Boivin GP, Kader SA, Caldwell CC, Degen SJ, Waltz SE. Short form Ron receptor is required for normal IFN-gamma production in concanavalin A-induced acute liver injury.  Am J Physiol (Gastrointest Liver Physiol) 292:G253-G261, 2007.

Worrell RT, Cuppoletti J, Matthews JB.  Colonic absorption and secretion.  In: Encyclopedia of Gastroenterology (Johnson LR, ed). Academic Press, in press.

Xiao C, Sartin J, Mulchahey JJ, Segar T, Sheriff S, Herman JP, Kasckow JW. Aging associated changes in amygdalar corticotropin-releasing hormone (CRH) and CRH-binding protein in Fischer 344 rats. Brain Res 1073-1074:325-331, 2006.

Xu J, Worrell RT, Li HC, Barone SL, Petrovic S, Amlal H, Soleimani M. Chloride/bicarbonate exchanger SLC26A7 is localized in endosomes in medullary collecting duct cells and is targeted to the basolateral membrane in hypertonicity and potassium depletion.  J Am Soc Nephrol 17:956-967, 2006.

Yahya A, Xiao C, Chance WT, Sheriff S. Up-regulation of neuropeptide Y4 receptor mRNA expression in the brainstem of refed rats following 48 hrs of food deprivation: Effect of leptin. Peptides 27:2731-2737, 2006.

Yu Z, Xia W, Wang H, Wang SC, Pan Y, Kwong KY, Hortobagyi GN, Hung MC. Antitumor activity on an Ets protein, PEA3, in breast cancer cell lines MDA-MB-361DYT2 and BT474M1. Molecular Carcinogenesis 45:667-675, 2006.

Zinser GM, Leonis MA, Toney K, Pathrose P, Thobe M, Kader SA, Peace BE, Beauman SR, Collins MH, Waltz SE.  Mammary-specific Ron receptor overexpression induces highly metastatic mammary tumors associated with beta-catenin activation.  Cancer Research 66:11967-11974, 2006.

 

Note:  To add a presentation or publication, please email to steve.wiesner@uc.edu.